Circuit Breaker
for Acne

Avène Cleanance Comedomed is a concentrate with plant-based active ingredients that offer an anti-relapse action.

It is suitable for acne-prone skin
regardless of age.

Reduce acne in 7 8 9 days


Reduce acne and prevent relapse acne formation. Easy to use and efficacy proven from 7 days1.

The ideal solution for people who want to see their skin improve as soon as possible!

92% of users are satisfied from 7 days3.
Anti-Relapse Actions4
With only eleven ingredients, this cutting-edge formula contains 25% Comedoclastin™, an innovative plant-based active ingredient derived from Milk Thistle.
blemishes from
7 days1
45%Clearer Skin After 2 Months2

    Exclusive Anti-Relapse action, reduces blackheads and mattifies.

  • GOOD

    Extra-fresh gel-cream, quick absorption, skin is silky and comfortable.


    2 pumps is enough for one use!


    Apply on affected area morning and evening after cleansing. Suitable for adults and adolescents

Avène Cleanance Comedomed - product image
1 Visible Pimple
100 Hidden Pimples

Did you know?

Many of us believe that targeting acne-prone skin involves taking care of the breakouts, spots and blackheads that are already on skin’s surface.

But have you heard about the hidden ‘invisible’ side of acne?


Natural Active Ingredient

Plant-based High
Concentration Formula


Stabilized extract derived from Milk Thistle helps visibly reduce and limit appearance of blemishes


Clinically shown by 150 studies to soothe, soften and calm the skin

The Acne Blocker


  • Mattifies & regulates the hyperproduction of sebum thanks to ComedoclastinTM a plant-based active ingredient derived from milk thistle seeds with patented properties 73% reduction in blackheads in 14 days
  • Lastingly decreases shine and diminishes skin impurities
  • Leaves the skin purified and refreshed

Avène Cleanance Cleansing Gel
NEW Limited Edition 400 ml*
* Exclusive at Watsons & Guardian


  • A pure, active and powerful water
  • Three proven actions: soothing, anti-irritant, softening
  • Unique mineral and organic composition (Aqua. dolomiae)
  • Efficacy demonstrated in more than 150 clinical studies

Avène Thermal Spring
Water Spray 300 ml


  • Light and easily absorbed aqueous gel texture with a non-oily and non-sticky finish
  • Apply morning and evening, alone or in combination with a treatment prescribed by the dermatologist
  • Fragrance-Free
  • Minimal ingredient with only 11 ingredients

Avène Cleanance Comedomed 30 ml


“I really like the simple ingredient list. I did not have any recurring pimples after a week of usage. Personally, I really like the fast absorption and quality of the serum.”


“It helps reduce the appearance of acne around my chin area. The texture is light and I love the non-greasy finish after applying! I applied on my entire face in the day and night. It can be used as a make up base too!”


“My face used to have a lot of pimples and blackheads. Now, it seems like it's better with lesser pimple scars. Overall, it's good and recommended! I would buy again after this bottle is empty!”


“This product really helps improve my skin and my red spots are slowly fading away.”

Verified authentic reviews collected from as of January 2022.

Will acne eventually go away on its own?

Learn more

This is sometimes true. In the case of hormonal acne linked to fluctuations during adolescence, it will gradually fade away around the age of 20. However, as time passes, adult acne is becoming more widespread. Some cases are linked to hormones, but others may be related to pollution, lifestyle or even an unbalanced microbiome. It is thus best to get your acne under control as soons as possible to get rid of it for good.

Does touching my acne make it worse?

Learn more

There is no need to worry about spreading bacteria in spots simply by touching your hand to your face. Spontaneously touching your cheek or gently rubbing your forehead has no impact on the severity of acne. However, squeezing spots and blemishes can affect it. Beware of inflammatory lesions full of pus and thus bacteria. Popping them increases may lead to permanent scarring on your skin.

Does junk food give you acne?

Learn more

Only in excess is it a problem. Excess fat is not an aggravating factor in acne. Simple sugars, however, those with a high glycemic index, contribute to the appearance and persistence of acne. This includes candy and other sweets, as well as hamburger buns and fries. On the other hand, green tea and its polyphenols appear to be beneficial to acne-prone skin, thanks to its ability to limit sebum production. Which is worth exploring futher.

Is sport bad for

Learn more

Too much sport has the opposite effect, it creates stress for the body. Too much testosterone is produced, hence too much sebum, which can cause new acne to appear. Generally speaking, 2 to 3 session a week is just about right! Make sure you shower after exercising! If perspiration stays in contact with the skin for too long, it encourages bad odors as well as the developement of bacteria, responsible for acne and blackheads. Also be aware of which towels you use, never share your towel and different towels should be used for your face, body and the workout bench!

1Clinical study found a significant reduction of blemishes observed under dermatological control with 51 subjects. Using Cleanance Comedomed twice a day for 56 days.

2A comparative study conducted on 36 subjects under dermatological control for 56 days. One untreated group (N=18), one group treated twice a day with Cleanance Comedomed (N=18).

3Self-evaluation at 7 days by 51 subjects. Use of Cleanance Comedomed twice a day for 56 days.

4International observational clinical study, 90% of patients without relapse of acne at 6 months, 48 subjects, 2 applications per day of Cleanance Comedomed alone for 6 months.

*Study based on internal data in more than 90 countries and an IQVIA survey in 7 countries.

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